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Neuroprotective Effects of Adenosine Monophosphate-Activated Protein Kinase Inhibition and Gene Deletion in Stroke

BACKGROUND AND PURPOSE: 5′ adenosine monophosphate-dependent protein kinase (AMPK) acts as a metabolic sensor. AMPK is elevated under ischemic conditions, but the role of AMPK in ischemic brain remains controversial. In this study, we examined the effects of AMPK inhibition using both pharmacologica...

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Détails bibliographiques
Auteurs principaux: Li, Jun, Zeng, Zhiyuan, Viollet, Benoit, Ronnett, Gabriele V., McCullough, Louise D.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637379/
https://ncbi.nlm.nih.gov/pubmed/17901380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.107.490904
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