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HIV-1 coreceptor usage prediction without multiple alignments: an application of string kernels

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) infects cells by means of ligand-receptor interactions. This lentivirus uses the CD4 receptor in conjunction with a chemokine coreceptor, either CXCR4 or CCR5, to enter a target cell. HIV-1 is characterized by high sequence variability. Nonethe...

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書目詳細資料
Main Authors: Boisvert, Sébastien, Marchand, Mario, Laviolette, François, Corbeil, Jacques
格式: Artigo
語言:Inglês
出版: BioMed Central 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637298/
https://ncbi.nlm.nih.gov/pubmed/19055831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-110
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