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Generation of Cyp17iCre transgenic mice and their application to conditionally delete estrogen receptor alpha (Esr1) from the ovary and testis

A transgenic mouse line that expresses iCre under regulation of the Cytochrome P(450) 17α-hydroxylase/17, 20-lyase (Cyp17) promoter was developed as a novel transgenic mouse model for the conditional deletion of genes specifically in the theca/interstitial cells of the ovary and Leydig cells of the...

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Bibliographische Detailangaben
Hauptverfasser: Bridges, Phillip J., Koo, Yongbum, Kang, Dong-Wook, Hudgins-Spivey, Susan, Lan, Zi-Jian, Xu, Xueping, DeMayo, Francesco, Cooney, Austin, Ko, CheMyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637183/
https://ncbi.nlm.nih.gov/pubmed/18781648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20428
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