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Distinct Functions of Activated Protein C Differentially Attenuate Acute Kidney Injury
Administration of activated protein C (APC) protects from renal dysfunction, but the underlying mechanism is unknown. APC exerts both antithrombotic and cytoprotective properties, the latter via modulation of protease-activated receptor-1 (PAR-1) signaling. We generated APC variants to study the rel...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Nephrology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637057/ https://ncbi.nlm.nih.gov/pubmed/19092124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008030294 |
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