Oxidation of extracellular cysteine/cystine redox state in bleomycin-induced lung fibrosis

Several lines of evidence indicate that depletion of glutathione (GSH), a critical thiol antioxidant, is associated with the pathogenesis of idiopathic pulmonary fibrosis (IPF). However, GSH synthesis depends on the amino acid cysteine (Cys), and relatively little is known about the regulation of Cy...

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Main Authors: Iyer, Smita S., Ramirez, Allan M., Ritzenthaler, Jeffrey D., Torres-Gonzalez, Edilson, Roser-Page, Susanne, Mora, Ana L., Brigham, Kenneth L., Jones, Dean P., Roman, Jesse, Rojas, Mauricio
格式: Artigo
語言:Inglês
出版: American Physiological Society 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636957/
https://ncbi.nlm.nih.gov/pubmed/18931052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90401.2008
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