The Glutathione Biosynthetic Pathway of Plasmodium Is Essential for Mosquito Transmission

Infection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species. Plasmodium spp. have thioredoxin and glutathione (GSH) systems that are thought to play a major role as...

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Detalhes bibliográficos
Main Authors: Vega-Rodríguez, Joel, Franke-Fayard, Blandine, Dinglasan, Rhoel R., Janse, Chris J., Pastrana-Mena, Rebecca, Waters, Andrew P., Coppens, Isabelle, Rodríguez-Orengo, José F., Jacobs-Lorena, Marcelo, Serrano, Adelfa E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636896/
https://ncbi.nlm.nih.gov/pubmed/19229315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000302
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