Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains

HCV entry into cells is a multi-step and slow process. It is believed that the initial capture of HCV particles by glycosaminoglycans and/or lipoprotein receptors is followed by coordinated interactions with the scavenger receptor class B type I (SR-BI), a major receptor of high-density lipoprotein...

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Main Authors: Dreux, Marlène, Dao Thi, Viet Loan, Fresquet, Judith, Guérin, Maryse, Julia, Zélie, Verney, Géraldine, Durantel, David, Zoulim, Fabien, Lavillette, Dimitri, Cosset, François-Loïc, Bartosch, Birke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636890/
https://ncbi.nlm.nih.gov/pubmed/19229312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000310
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