Dual Role of Sp3 Transcription Factor as an Inducer of Apoptosis and a Marker of Tumour Aggressiveness

BACKGROUND: The ambiguous role of transcription factor Sp3 for tumour progression is still debated since it was described as a transcriptional repressor or activator. Here we tried to decipher the molecular mechanisms implicated in Sp3 accumulation observed in aggressive tumours. METHODOLOGY: We gen...

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Autors principals: Essafi-Benkhadir, Khadija, Grosso, Sébastien, Puissant, Alexandre, Robert, Guillaume, Essafi, Makram, Deckert, Marcel, Chamorey, Emmanuel, Dassonville, Olivier, Milano, Gérard, Auberger, Patrick, Pagès, Gilles
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636865/
https://ncbi.nlm.nih.gov/pubmed/19212434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004478
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