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Distinct functions for the catalytic and hemopexin domains of a Drosophila matrix metalloproteinase
Human matrix metalloproteinases (MMPs) are believed to contribute to tumor progression. Therapies based on inhibiting the catalytic domain of MMPs have been unsuccessful, but these studies raise the question of whether other MMP domains might be appropriate targets. The genetic dissection of domain...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2636737/ https://ncbi.nlm.nih.gov/pubmed/19196956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804171106 |
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