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CD4 deficits and Disease Course Acceleration can be driven by a collapse of the CD8 response in SIV-infected Rhesus Macaques
OBJECTIVES: Defects in memory CD4+ T cells correlate with development of AIDS in SIV-infected monkeys, but the early events leading to these deficits are unknown. We explored the role of SIV-specific and CD8 cells in the determination of CD4 failure and rapid disease course. DESIGN AND METHODS: Usin...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2636707/ https://ncbi.nlm.nih.gov/pubmed/18614867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283052fb5 |
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