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Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin

Genetic and biochemical evidence suggests a functional link between human 12R-lipoxygenase (12R-LOX) and epidermal lipoxygenase-3 (eLOX3) in normal differentiation of the epidermis; LOX-derived fatty acid hydroperoxide is isomerized by the atypical eLOX3 into a specific epoxyalcohol that is a potent...

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Autori principali: Yu, Zheyong, Schneider, Claus, Boeglin, William E., Brash, Alan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636205/
https://ncbi.nlm.nih.gov/pubmed/17045234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2006.09.002
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