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Phosphatase of Regenerating Liver-3 Localizes to Cyto-Membrane and Is Required for B16F1 Melanoma Cell Metastasis In Vitro and In Vivo

BACKGROUND: Phosphatase of regenerating liver-3 (PRL-3) is a member of the novel phosphatases of regenerating liver family, characterized by one protein tyrosine phosphatase active domain and a C-terminal prenylation (CCVM) motif. Though widely proposed to facilitate metastasis in many cancer types,...

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Detalhes bibliográficos
Main Authors: Song, Ran, Qian, Feng, Li, Yu-Pei, Sheng, Xia, Cao, Shao-Xian, Xu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635958/
https://ncbi.nlm.nih.gov/pubmed/19214221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004450
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