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Towards Accurate Residue-Residue Hydrophobic Contact Prediction for Alpha Helical Proteins Via Integer Linear Optimization

A new optimization-based method is presented to predict the hydrophobic residue contacts in α-helical proteins. The proposed approach uses a high resolution distance dependent force field to calculate the interaction energy between different residues of a protein. The formulation predicts the hydrop...

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Detalhes bibliográficos
Main Authors: Rajgaria, R., McAllister, S. R., Floudas, C. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635923/
https://ncbi.nlm.nih.gov/pubmed/18767158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22202
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