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Antibody to Langerin/CD207 localizes large numbers of CD8α(+) dendritic cells to the marginal zone of mouse spleen

Dendritic cells (DCs) are strategically positioned to take up antigens and initiate adaptive immunity. One DC subset expresses CD8αα in mice and is specialized to capture dying cells and process antigens for MHC class I “cross-presentation.” Because CD8(+) DCs also express DEC205/CD205, which is loc...

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Detalhes bibliográficos
Main Authors: Idoyaga, Juliana, Suda, Nao, Suda, Koji, Park, Chae Gyu, Steinman, Ralph M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635812/
https://ncbi.nlm.nih.gov/pubmed/19168629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812247106
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