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Energy Restriction Impairs Natural Killer Cell Function and Increases the Severity of Influenza Infection in Young Adult Male C57BL/6 Mice

Energy restriction (ER) without malnutrition extends lifespan in mice and postpones age-related changes in immunity. However, we have previously shown that aged (22 mo old) ER mice exhibit increased mortality, impaired viral clearance, and reduced natural killer (NK) cell cytotoxicity following infl...

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Detalhes bibliográficos
Main Authors: Ritz, Barry W., Aktan, Idil, Nogusa, Shoko, Gardner, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635521/
https://ncbi.nlm.nih.gov/pubmed/18936230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.108.093633
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