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Role of Sirtuin Histone Deacetylase SIRT1 in Prostate Cancer: A TARGET FOR PROSTATE CANCER MANAGEMENT VIA ITS INHIBITION?

Prostate cancer (PCa) is a major age-related malignancy, and according to estimates from the American Cancer Society, a man's chance of developing this cancer significantly increases with increasing age, from 1 in 10,149 by age 39 to 1 in 38 by age 59 to 1 in 7 by age 70. Therefore, it is impor...

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Bibliographic Details
Main Authors: Jung-Hynes, Brittney, Nihal, Minakshi, Zhong, Weixiong, Ahmad, Nihal
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635052/
https://ncbi.nlm.nih.gov/pubmed/19075016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807869200
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