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Cytokine-induced Signaling Networks Prioritize Dynamic Range over Signal Strength
Signaling networks respond to diverse stimuli, but how the state of the signaling network is relayed to downstream cellular responses is unclear. We modeled how incremental activation of signaling molecules is transmitted to control apoptosis as a function of signal strength and dynamic range. A lin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635014/ https://ncbi.nlm.nih.gov/pubmed/18957207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.08.034 |
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