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siRNA as a tool for investigating organogenesis: The pitfalls and the promises

Removing the function of a specific gene from a developing organ, by making a ‘knockout’ mouse, is a powerful method for analyzing the molecular pathways that control organogenesis. The technique is expensive, though, in terms of time and money, and complex strategies for producing conditional knock...

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Detalhes bibliográficos
Main Authors: Lee, Wen-Chin, Berry, Rachel, Hohenstein, Peter, Davies, Jamie
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634977/
https://ncbi.nlm.nih.gov/pubmed/19279730
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