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An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity

Type I IFNs were discovered as the primary antiviral cytokines and are now known to serve critical functions in host defense against bacterial pathogens. Accordingly, established mediators of IFN antiviral activity may mediate previously unrecognized antibacterial functions. RNase-L is the terminal...

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Dettagli Bibliografici
Autori principali: Li, Xiao-Ling, Ezelle, Heather J., Kang, Tae-Jin, Zhang, Lei, Shirey, Kari Ann, Harro, Janette, Hasday, Jeffrey D., Mohapatra, Saroj K., Crasta, Oswald R., Vogel, Stefanie N., Cross, Alan S., Hassel, Bret A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634919/
https://ncbi.nlm.nih.gov/pubmed/19075243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807265105
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