טוען...

Use of Tc-99m Mebrofenin as a Clinical Probe to Assess Altered Hepatobiliary Transport: Integration of In Vitro, Pharmacokinetic Modeling, and Simulation Studies

PURPOSE: Transport of the hepatobiliary scintigraphy agent Tc-99m mebrofenin (MEB) was characterized, and simulation studies were conducted to examine the effects of altered hepatic transport on MEB pharmacokinetics in humans. METHODS: MEB transport was investigated in Xenopus laevis oocytes express...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ghibellini, Giulia, Leslie, Elaine M., Pollack, Gary M., Brouwer, Kim L.R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634848/
https://ncbi.nlm.nih.gov/pubmed/18509604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-008-9597-0
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