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γ-Secretase Activity Modulates Store-Operated Ca(2+) Entry into Rat Sensory Neurons
Presenilin-1 is required for γ-secretase activity, which participates in Notch receptor processing, the pathogenesis of Alzheimer's disease and the modulation of Ca(2+) signaling. We tested the hypothesis that γ-secretase proteolytic activity modulates store-operated Ca(2+) entry (SOCE) in rat...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634821/ https://ncbi.nlm.nih.gov/pubmed/19114088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.12.031 |
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