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Direct effects of doxorubicin on skeletal muscle contribute to fatigue
Chemotherapy-induced fatigue is a multidimensional symptom. Oxidative stress has been proposed as a working mechanism for anthracycline-induced cardiotoxicity. In this study, doxorubicin (DOX) was tested on skeletal muscle function. Doxorubicin induced impaired ex vivo skeletal muscle relaxation fol...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634729/ https://ncbi.nlm.nih.gov/pubmed/19165199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604858 |
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