Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin

Heat shock protein 90 (Hsp90) has been demonstrated to protect oncogenic variants of signalling molecules from degradation and may consequently serve as a therapeutic target for the treatment of oesophageal cancer for which adequate therapy is often lacking. We studied the expression of Hsp90 in tum...

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Hlavní autoři: Wu, X, Wanders, A, Wardega, P, Tinge, B, Gedda, L, Bergstrom, S, Sooman, L, Gullbo, J, Bergqvist, M, Hesselius, P, Lennartsson, J, Ekman, S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634703/
https://ncbi.nlm.nih.gov/pubmed/19142186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604855
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