An adenosine A(2A) antagonist injected in the NTS reverses thermal prolongation of the LCR in decerebrate piglets

Hyperthermia prolongs the laryngeal chemoreflex (LCR). Under normothermic conditions, adenosine antagonists shorten and adenosine A(2A) (Ad-A(2A)) agonists prolong the LCR. Therefore, we tested the hypothesis that SCH-58261, an Ad-A(2A) receptor antagonist, would prevent thermal prolongation of the...

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Bibliographic Details
Main Authors: Xia, Luxi, Bartlett, Donald, Leiter, J.C.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634599/
https://ncbi.nlm.nih.gov/pubmed/18775519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2008.08.002
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