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Ceruloplasmin fragmentation is implicated in ‘free’ copper deregulation of Alzheimer's disease

A dysfunction in copper homeostasis seems to occur in Alzheimer's disease (AD). We recently demonstrated that an excess of non-ceruloplasmin-copper (i.e., ‘free’ copper) correlates with the main functional and anatomical deficits as well as the cerebrospinal markers of the disease, thus suggest...

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Autores principales: Squitti, Rosanna, Quattrocchi, Carlo C, Salustri, Carlo, Rossini, Paolo M
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634417/
https://ncbi.nlm.nih.gov/pubmed/19164917
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