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INCREASED SULT1E1 ACTIVITY IN HEPG2 HEPATOCYTES DECREASES GROWTH HORMONE STIMULATION OF STAT5B PHOSPHORYLATION

Mouse models of cystic fibrosis (CF) display increased sulfotransferase 1E1 (SULT1E1) activity in hepatocytes of cystic fibrosis transmembrane receptor (CFTR)-deficient animals. SULT1E1 is responsible for the sulfation and inactivation of β-estradiol (E2) at physiological concentrations. IGF-1 messa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Li, He, Dongning, Wilborn, Teresa W., Falany, Josie L., Falany, Charles N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633718/
https://ncbi.nlm.nih.gov/pubmed/18831980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2008.09.002
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