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Computational Simulations of the Early Steps of Protein Aggregation

There is strong evidence that the oligomers of key proteins, formed during the early steps of aggregation, could be the primary toxic species associated with human neurodegenerative diseases, such as Alzheimer's and prion diseases. Here, we review recent progress in the development of computati...

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Библиографические подробности
Главные авторы: Wei, Guanghong, Mousseau, Normand, Derreumaux, Philippe
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633700/
https://ncbi.nlm.nih.gov/pubmed/19164927
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