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Image-guided, noninvasive, spatiotemporal control of gene expression

Spatiotemporal control of transgene expression is of paramount importance in gene therapy. Here, we demonstrate the use of magnetic resonance temperature imaging (MRI)-guided, high-intensity focused ultrasound (HIFU) in combination with a heat-inducible promoter [heat shock protein 70 (HSP70)] for t...

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Autores principales: Deckers, Roel, Quesson, Bruno, Arsaut, Josette, Eimer, Sandrine, Couillaud, Franck, Moonen, Chrit T. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633569/
https://ncbi.nlm.nih.gov/pubmed/19164593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806936106
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