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Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis

Osteoarthritis (OA) is the most common joint disease and typically begins with an aging-related disruption of the articular cartilage surface. Mechanisms leading to the aging-related cartilage surface degeneration remain to be determined. Here, we demonstrate that nonhistone chromatin protein high-m...

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Main Authors: Taniguchi, Noboru, Caramés, Beatriz, Ronfani, Lorenza, Ulmer, Ulrich, Komiya, Setsuro, Bianchi, Marco E., Lotz, Martin
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633567/
https://ncbi.nlm.nih.gov/pubmed/19139395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806062106
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