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Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis

Osteoarthritis (OA) is the most common joint disease and typically begins with an aging-related disruption of the articular cartilage surface. Mechanisms leading to the aging-related cartilage surface degeneration remain to be determined. Here, we demonstrate that nonhistone chromatin protein high-m...

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Main Authors: Taniguchi, Noboru, Caramés, Beatriz, Ronfani, Lorenza, Ulmer, Ulrich, Komiya, Setsuro, Bianchi, Marco E., Lotz, Martin
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633567/
https://ncbi.nlm.nih.gov/pubmed/19139395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806062106
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