Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis

Osteoarthritis (OA) is the most common joint disease and typically begins with an aging-related disruption of the articular cartilage surface. Mechanisms leading to the aging-related cartilage surface degeneration remain to be determined. Here, we demonstrate that nonhistone chromatin protein high-m...

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Bibliografiske detaljer
Main Authors: Taniguchi, Noboru, Caramés, Beatriz, Ronfani, Lorenza, Ulmer, Ulrich, Komiya, Setsuro, Bianchi, Marco E., Lotz, Martin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633567/
https://ncbi.nlm.nih.gov/pubmed/19139395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806062106
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