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Nitric oxide and TNF-α trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice
Recombinase-activating gene-2-deficient (Rag2(−/−)) mice lacking functional lymphocytes provide a useful model of chronic inflammatory bowel disease-emulating events in human colon cancer. Infection of Rag2(−/−) mice with Helicobacter hepaticus led to accumulation of macrophages and neutrophils in t...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633549/ https://ncbi.nlm.nih.gov/pubmed/19164562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812347106 |
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