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Chromatin assembly factors Asf1 and CAF-1 have overlapping roles in deactivating the DNA damage checkpoint when DNA repair is complete

In response to a DNA double-strand break (DSB), chromatin is rapidly modified by the damage dependent checkpoint kinases. Also, disassembly of chromatin occurs at the break site. The damage-induced modification of chromatin structure is involved in the maintenance of the checkpoint. However, it has...

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Detalhes bibliográficos
Main Authors: Kim, Jung-Ae, Haber, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633530/
https://ncbi.nlm.nih.gov/pubmed/19164567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812578106
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