The Extracellular Domain of Lrp5/6 Inhibits Noncanonical Wnt Signaling In Vivo

Lrp5/6 are crucial coreceptors for Wnt/β-catenin signaling, a pathway biochemically distinct from noncanonical Wnt signaling pathways. Here, we examined the possible participation of Lrp5/6 in noncanonical Wnt signaling. We found that Lrp6 physically interacts with Wnt5a, but that this does not lead...

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Main Authors: Bryja, Vitezslav, Andersson, Emma R., Schambony, Alexandra, Esner, Milan, Bryjová, Lenka, Biris, Kristin K., Hall, Anita C., Kraft, Bianca, Cajanek, Lukas, Yamaguchi, Terry P., Buckingham, Margaret, Arenas, Ernest
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2009
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633404/
https://ncbi.nlm.nih.gov/pubmed/19056682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-07-0711
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