Neutralization of tetanus toxin by distinct monoclonal antibodies binding to multiple epitopes on the toxin molecule.

Fifty-seven hybridomas producing antibodies to tetanus toxoid or to the Ibc or B-IIb fragment of the toxin were isolated independently. Competitive inhibition studies demonstrated that monoclonal antibodies from mice immunized with the toxoid bound to at least 20 different epitopes on the toxoid mol...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Volk, W A, Bizzini, B, Snyder, R M, Bernhard, E, Wagner, R R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC263337/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6205994/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.45.3.604-609.1984
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