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Elevated Asymmetric Dimethylarginine Alters Lung Function and Induces Collagen Deposition in Mice

Increasing evidence suggests that lung mechanics and structure are maintained in part by an intimate balance between the L-arginine–metabolizing enzymes nitric oxide synthase (NOS) and arginase. Asymmetric dimethylarginine (ADMA) is a competitive endogenous inhibitor of NOS. The role of ADMA in the...

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Autors principals: Wells, Sandra M., Buford, Mary C., Migliaccio, Christopher T., Holian, Andrij
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633140/
https://ncbi.nlm.nih.gov/pubmed/18703795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0148OC
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