Ctk1 promotes dissociation of basal transcription factors from elongating RNA polymerase II

As RNA polymerase II (RNApII) transitions from initiation to elongation, Mediator and the basal transcription factors TFIID, TFIIA, TFIIH, and TFIIE remain at the promoter as part of a scaffold complex, whereas TFIIB and TFIIF dissociate. The yeast Ctk1 kinase associates with elongation complexes an...

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Main Authors: Ahn, Seong Hoon, Keogh, Michael-Christopher, Buratowski, Stephen
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632940/
https://ncbi.nlm.nih.gov/pubmed/19131970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.280
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