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Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: case study of primary immunodeficiencies

Disease gene identification is still a challenge despite modern high-throughput methods. Many diseases are very rare or lethal and thus cannot be investigated with traditional methods. Several in silico methods have been developed but they have some limitations. We introduce a new method that combin...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ortutay, Csaba, Vihinen, Mauno
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632920/
https://ncbi.nlm.nih.gov/pubmed/19073697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn982
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