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RAD54 controls access to the invading 3′-OH end after RAD51-mediated DNA strand invasion in homologous recombination in Saccharomyces cerevisiae

Rad51 is a key protein in homologous recombination performing homology search and DNA strand invasion. After DNA strand exchange Rad51 protein is stuck on the double-stranded heteroduplex DNA product of DNA strand invasion. This is a problem, because DNA polymerase requires access to the invading 3′...

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Autors principals: Li, Xuan, Heyer, Wolf-Dietrich
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632917/
https://ncbi.nlm.nih.gov/pubmed/19074197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn980
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