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An affinity-based scoring scheme for predicting DNA-binding activities of modularly assembled zinc-finger proteins
Zinc-finger proteins (ZFPs) have long been recognized for their potential to manipulate genetic information because they can be engineered to bind novel DNA targets. Individual zinc-finger domains (ZFDs) bind specific DNA triplet sequences; their apparent modularity has led some groups to propose me...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632909/ https://ncbi.nlm.nih.gov/pubmed/19056825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn962 |
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