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Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p

Appropriate control of the chromosome end-replicating enzyme telomerase is crucial for maintaining telomere length and genomic stability. The essential telomeric DNA-binding protein Cdc13p both positively and negatively regulates telomere length in budding yeast. Here we test the effect of purified...

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Hlavní autoři: Zappulla, David C., Roberts, Jennifer N., Goodrich, Karen J., Cech, Thomas R., Wuttke, Deborah S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632905/
https://ncbi.nlm.nih.gov/pubmed/19043074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn830
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