Interleukin-15 stimulates macrophages to activate CD4(+) T cells: a role in the pathogenesis of rheumatoid arthritis?

Interleukin-15 (IL-15) is a proinflammatory cytokine that is overexpressed in rheumatoid arthritis (RA), a disease characterized by activation of monocytes/macrophages (MΦ), and by expansion of autoreactive CD4(+) T cells. We hypothesized that IL-15 plays a major role for this expansion of CD4(+) T...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rückert, René, Brandt, Katja, Ernst, Martin, Marienfeld, Kathleen, Csernok, Elena, Metzler, Claudia, Budagian, Vadim, Bulanova, Elena, Paus, Ralf, Bulfone-Paus, Silvia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2009
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632696/
https://ncbi.nlm.nih.gov/pubmed/18557790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02878.x
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