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Depletion of CD8(+) T cells enhances airway remodelling in a rodent model of asthma

Airway remodelling is induced by persistent airway inflammation and may lead to severe asthma. T cells play a pivotal role in asthmatic airway inflammation but their role in remodelling is poorly understood. Although previous studies have revealed that CD8(+) T cells inhibit the late airway response...

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Detalhes bibliográficos
Main Authors: Tsuchiya, Kimitake, Isogai, Susumu, Tamaoka, Meiyo, Inase, Naohiko, Akashi, Takumi, Martin, James G, Yoshizawa, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632694/
https://ncbi.nlm.nih.gov/pubmed/18564065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02876.x
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