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Optimizing Imatinib Mesylate Treatment in Gastrointestinal Stromal Tumors

Improvements in the understanding of molecular oncogenesis and mechanisms of drug resistance have presented new opportunities for the treatment of gastrointestinal stromal tumors (GIST). In particular, the discovery of c-kit genomic mutations in GIST and the development of targeted therapy with imat...

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Autori principali: Jiang, Yixing, Ming, Lee, Montero, Alberto J., Kimchi, Eric, Nikfarjam, Mehrdad, Staveley-O’Carroll, Kevin F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Society of Gastrointestinal Oncology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632557/
https://ncbi.nlm.nih.gov/pubmed/19259308
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