Phage Lysin LysK Can Be Truncated to Its CHAP Domain and Retain Lytic Activity against Live Antibiotic-Resistant Staphylococci

A truncated derivative of the phage endolysin LysK containing only the CHAP (cysteine- and histidine-dependent amidohydrolase/peptidase) domain exhibited lytic activity against live clinical staphylococcal isolates, including methicillin-resistant Staphylococcus aureus. This is the first known repor...

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Main Authors: Horgan, Marianne, O’Flynn, Gary, Garry, Jennifer, Cooney, Jakki, Coffey, Aidan, Fitzgerald, Gerald F., Ross, R. Paul, McAuliffe, Olivia
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Physiology and Biotechnology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632115/
https://ncbi.nlm.nih.gov/pubmed/19047377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01831-08
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