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Streptococcus pneumoniae Capsular Serotype 19F Is More Resistant to C3 Deposition and Less Sensitive to Opsonophagocytosis than Serotype 6B

The polysaccharide capsule is a major virulence mechanism of Streptococcus pneumoniae, shielding the bacterium from phagocytes. Capsule types may differ in their abilities to resist immune defense. Antibody-mediated complement activation and opsonophagocytosis are crucial in protection against pneum...

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Bibliografske podrobnosti
Main Authors: Melin, Merit, Jarva, Hanna, Siira, Lotta, Meri, Seppo, Käyhty, Helena, Väkeväinen, Merja
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632042/
https://ncbi.nlm.nih.gov/pubmed/19047408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01186-08
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