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Sumoylation Regulates the Transcriptional Activity of MafA in Pancreatic β Cells
MafA is a transcriptional regulator expressed primarily in pancreatic β cells. It binds to the RIPE3b/C1-binding site within the ins gene promoter, which plays a critical role in regulating ins gene expression in response to glucose. Here, we show that MafA is post-translationally modified by the sm...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631948/ https://ncbi.nlm.nih.gov/pubmed/19029092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806286200 |
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