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Anthrax Edema Toxin Inhibits Nox1-Mediated Formation of Reactive Oxygen Species by Colon Epithelial Cells

One major route of intoxication by Bacillus anthracis (anthrax) spores is via their ingestion and subsequent uptake by the intestinal epithelium. Anthrax edema toxin (ETx) is an adenylate cyclase that causes persistent elevation of cAMP in intoxicated cells. NADPH oxidase enzymes (Nox1–Nox5, Duox1 a...

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Main Authors: Kim, Jun-Sub, Bokoch, Gary M.
格式: Artigo
語言:Inglês
出版: S. Karger AG 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631933/
https://ncbi.nlm.nih.gov/pubmed/20046221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151481
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