Anthrax Edema Toxin Inhibits Nox1-Mediated Formation of Reactive Oxygen Species by Colon Epithelial Cells

One major route of intoxication by Bacillus anthracis (anthrax) spores is via their ingestion and subsequent uptake by the intestinal epithelium. Anthrax edema toxin (ETx) is an adenylate cyclase that causes persistent elevation of cAMP in intoxicated cells. NADPH oxidase enzymes (Nox1–Nox5, Duox1 a...

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Bibliographic Details
Main Authors: Kim, Jun-Sub, Bokoch, Gary M.
Format: Artigo
Language:Inglês
Published: S. Karger AG 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631933/
https://ncbi.nlm.nih.gov/pubmed/20046221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151481
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