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Anthrax Edema Toxin Inhibits Nox1-Mediated Formation of Reactive Oxygen Species by Colon Epithelial Cells

One major route of intoxication by Bacillus anthracis (anthrax) spores is via their ingestion and subsequent uptake by the intestinal epithelium. Anthrax edema toxin (ETx) is an adenylate cyclase that causes persistent elevation of cAMP in intoxicated cells. NADPH oxidase enzymes (Nox1–Nox5, Duox1 a...

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Autors principals: Kim, Jun-Sub, Bokoch, Gary M.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631933/
https://ncbi.nlm.nih.gov/pubmed/20046221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151481
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